Cortical stimulation in pharmacoresistant focal epilepsies
نویسندگان
چکیده
منابع مشابه
Cortical involvement in focal epilepsies with epileptic spasms.
The pathophysiological mechanisms of epileptic spasms are still poorly understood. The role of subcortical structures has been suggested on the basis of non-localized EEG features and from experimental data. The description of asymmetric spasms associated with lateralized EEG patterns has challenged this view and raises the possibility of a cortical origin. This study investigated the cortical ...
متن کاملO15: Lateralizing and Localizing Findings in Focal Epilepsies
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملmTOR pathway in familial focal epilepsies
An increasingly recognized role of genes encoding components of the mammalian Target Of Rapamycin (mTOR) signal transduction pathway has recently emerged among familial focal epilepsies. Loss-of-function mutations in the Dishevelled, Egl-10 and Pleckstrin Domain Containing protein 5 (DEPDC5) gene, and lately in the genes encoding Nitrogen Permease Regulator Like 2 and 3 proteins (NPRL2 and NPRL...
متن کاملNMDA receptor binding in focal epilepsies
OBJECTIVE To demonstrate altered N-methyl-d-aspartate (NMDA) receptor availability in patients with focal epilepsies using positron emission tomography (PET) and [(18)F]GE-179, a ligand that selectively binds to the open NMDA receptor ion channel, which is thought to be overactive in epilepsy. METHODS Eleven patients (median age 33 years, 6 males) with known frequent interictal epileptiform d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bioelectronic Medicine
سال: 2020
ISSN: 2332-8886
DOI: 10.1186/s42234-020-00054-4